| TOXICITY EVALUATION USING HUMAN CELLS IN WATER TREATMENT PROCESSES |
| Berm-Soo Kim1, Myung-Ho Han1†, and Man-Woo Huh2 |
1Dept. of Industrial Chemistry, Kyungil University, Kyungsan 712-701, Korea
2Dept. of Textile and Fashion Technology, Kyungil University, Kyungsan 712-701, Korea |
Corresponding Author:
Myung-Ho Han ,Tel: +82-53-850-7186, Fax: +82-53-851-9523, Email: mhhan@kiu.ac.kr
|
|
Received: February 13, 2003; Accepted: July 13, 2003. |
|
|
Share : 
|
| ABSTRACT |
|
Changes in cytotoxicity and mutagenicity of pesticides (7 pesticides in the quality standard for water), spiked in groundwater, were studied using bioassays by ozonation and activated carbon adsorption. It was shown that the mutagenicity of bentiocarb-added water increased with ozonation time, however, it was not the case with water that contains either dimethyl 2,2-dichlorovinylphosphate (DDVP) or dimethyl 4-nitro-m- tolyl phosphorothioate (MEP) In terms of cytotoxicity, the growth inhibition for human diploid cell (TIG-1) in bentiocarb-added water increased with ozonation time. The cytotoxicity for DDVP-added water remained intact after ozonation, and it was not removed by the additional process of activated carbon adsorption. The changes in pesticides concentration by ozonation were not related to the changes of mutagenicity and cytotoxicity. It was also shown that the mutagenicity and cytotoxicity were varied with the reaction byproducts. Thus, to evaluate toxicity of water on humans, both the cytotoxicity and mutagenicity should be considered, at least in water quality management. |
| Keywords:
cytotoxicity | mutagenicity | ozonation | human diploid cell (TIG-1) |
|
|
|
PDF Links
Full text via DOI
Download Citation 
